Use: Grammar
Although / though / even though / in spite of / despite

Structure:
After although use a subject + verb
Sometimes we use though instead of although
Even though is a stronger form of though
After in spite of or despite use a noun or pronoun or implied noun. (subject)
In spite of and despite are the same.

Examples:
Although they were discussing layoffs, he knew he would not be fired.
Even though he was caught in the middle, he did not care.
In spite of the mega merger, he remained at the helm.
Despite his efforts he failed.